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E-AB-92306

ZNF521 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:
E-AB-92306
Additional Names:
Evi3,EHZF
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ZNF521
Uniprot:
Q96K83
Synonyms:
early hematopoietic zinc finger protein;EHZF;Evi3;LYST-interacting protein 3;zinc finger protein 521
Extra Details:
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage, this interaction preventing EBF1 to bind DNA and activate target genes.
Shipping Conditions:
Blue Ice