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E-AB-92258

ADRB2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92258
Additional Names:
ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human ADRB2
Uniprot:
P07550
Synonyms:
ADRB2R;ADRBR;adrenergic, beta-2-, receptor, surface;adrenoceptor beta 2 surface;B2AR;BAR;beta-2 adrenergic receptor;beta-2 adrenoceptor;beta-2 adrenoreceptor;BETA2AR;catecholamine receptor
Extra Details:
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Shipping Conditions:
Blue Ice