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E-AB-92250

Claudin 6 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92250
Additional Names:
Claudin-6,Claudin6,CLD6,CLDN 6,CLDN6,OTTHUMP00000159248,Skullin 2,Skullin,UNQ757/PRO1488
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human Claudin 6
Uniprot:
P56747
Synonyms:
claudin-6;skullin
Extra Details:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
Shipping Conditions:
Blue Ice