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E-AB-92166

PLP1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92166
Additional Names:
GPM6C,HLD1,MMPL,PLP,PLP/DM20,PLP1,PMD,SPG2
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PLP1
Uniprot:
P60201
Synonyms:
GPM6C;HLD1;lipophilin;major myelin proteolipid protein;MMPL;myelin proteolipid protein;PLP;PLP/DM20;PMD;SPG2
Extra Details:
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
Shipping Conditions:
Blue Ice