E-AB-92150
ITPR2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92150
- Additional Names:
- ANHD,CFAP48,INSP3R2,IP3R2,ITPR2
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ITPR2
- Uniprot:
- Q14571
- Synonyms:
- ANHD;CFAP48;cilia and flagella associated protein 48;inositol 1,4,5-trisphosphate receptor type 2;INSP3R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;Type 2 inositol 1,4,5-trisphosphate receptor;type 2 InsP3 receptor
- Extra Details:
- The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
- Shipping Conditions:
- Blue Ice