E-AB-92142
KCNQ2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92142
- Additional Names:
- BFNC,EBN,EBN1,ENB1,HNSPC,KCNA11,KCNQ2,KV7.2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KCNQ2
- Uniprot:
- O43526
- Synonyms:
- BFNC;DEE7;EBN;EBN1;ENB1;HNSPC;KCNA11;KQT-like 2;KV7.2;neuroblastoma-specific potassium channel subunit alpha KvLQT2;potassium channel, voltage gated KQT-like subfamily Q, member 2;potassium voltage-gated channel subfamily KQT member 2;voltage-gated potassium channel subunit Kv7.2
- Extra Details:
- The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice