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E-AB-92122

SUPT16H Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92122
Additional Names:
FACTP140, SPT16, SPT16/CDC68,CDC68
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SUPT16H
Uniprot:
Q9Y5B9
Synonyms:
CDC68;chromatin-specific transcription elongation factor 140 kDa subunit;facilitates chromatin remodeling 140 kDa subunit;facilitates chromatin transcription complex subunit SPT16;FACT 140 kDa subunit;FACT complex subunit SPT16;FACTP140;hSPT16;NEDDFAC;SPT16;SPT16/CDC68;suppressor of Ty 16 homolog
Extra Details:
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, this gene encodes the 140 kDa subunit.
Shipping Conditions:
Blue Ice