E-AB-92079
Topors Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92079
- Additional Names:
- AW105885,LUN,TP53BPL,Topors,p53BP3/LUN
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of mouse Topors
- Uniprot:
- Q80Z37
- Synonyms:
- AW105885;E3 ubiquitin-protein ligase Topors;LUN;p53-binding protein 3;p53BP3;p53BP3/LUN;RING-type E3 ubiquitin transferase Topors;SUMO1-protein E3 ligase Topors;topoisomerase 1-binding RING finger;topoisomerase I-binding arginine/serine-rich protein;topoisomerase I-binding RING finger protein;TP53BPL;tumor suppressor p53-binding protein 3
- Extra Details:
- Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.
- Shipping Conditions:
- Blue Ice