E-AB-92076
KBTBD8 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92076
- Additional Names:
- KBTBD8,TA-KRP,TAKRP
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KBTBD8
- Uniprot:
- Q8NFY9
- Synonyms:
- kelch repeat and BTB (POZ) domain containing 8;kelch repeat and BTB domain-containing protein 8;T-cell activation kelch repeat protein;TA-KRP;TAKRP
- Extra Details:
- Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
- Shipping Conditions:
- Blue Ice