E-AB-92074
PANK2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92074
- Additional Names:
- C20orf48,HARP,HSS,NBIA1,PANK2,PKAN
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human PANK2
- Uniprot:
- Q9BZ23
- Synonyms:
- C20orf48;Hallervorden-Spatz syndrome;HARP;HSS;NBIA1;pantothenate kinase 2, mitochondrial;pantothenate kinase-associated neurodegeneration;pantothenic acid kinase 2;PKAN
- Extra Details:
- This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice