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E-AB-92066

TSHZ3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92066
Additional Names:
TSH3,TSHZ3,ZNF537
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TSHZ3
Uniprot:
Q63HK5
Synonyms:
teashirt family zinc finger 3;teashirt homolog 3;TSH3;zinc finger protein 537;ZNF537
Extra Details:
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer&apos,s disease in human patients. [provided by RefSeq, Jul 2016]
Shipping Conditions:
Blue Ice