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E-AB-92033

FZD8 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92033
Additional Names:
FZ-8,FZD8,hFZ8
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human FZD8
Uniprot:
Q9H461
Synonyms:
frizzled 8, seven transmembrane spanning receptor;frizzled family receptor 8;frizzled homolog 8;frizzled-8;FZ-8;hFZ8
Extra Details:
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice