E-AB-91995
BTBD7 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91995
- Additional Names:
- BTBD7,FUP1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BTBD7
- Uniprot:
- Q9P203
- Synonyms:
- BTB (POZ) domain containing 7;BTB/POZ domain-containing protein 7;FUP1
- Extra Details:
- Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity.
- Shipping Conditions:
- Blue Ice