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E-AB-91952

ACVRL1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-91952
Additional Names:
ACVRL1,ACVRLK1,ALK-1,ALK1,HHT,HHT2,ORW2,SKR3,TSR-I
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ACVRL1
Uniprot:
P37023
Synonyms:
activin A receptor type II-like 1;activin A receptor type IL;activin A receptor, type II-like kinase 1;Activin receptor-like kinase 1;ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;serine/threonine-protein kinase receptor R3;SKR3;TGF-B superfamily receptor type I;TSR-I
Extra Details:
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Shipping Conditions:
Blue Ice