E-AB-91897
PRDM12 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91897
- Additional Names:
- HSAN8,PFM9,PRDM12
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PRDM12
- Uniprot:
- Q9H4Q4
- Synonyms:
- HSAN8;PFM9;PR domain containing 12;PR domain zinc finger protein 12;PR domain-containing protein 12
- Extra Details:
- This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN&apos,s) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]
- Shipping Conditions:
- Blue Ice