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E-AB-91870

PLA2G3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-91870
Additional Names:
GIII-SPLA2,PLA2G3,SPLA2III,sPLA2-III
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human PLA2G3
Uniprot:
Q9NZ20
Synonyms:
GIII-SPLA2;group 3 secretory phospholipase A2;group III secreted phospholipase A2;Group III secretory phospholipase A2;phosphatidylcholine 2-acylhydrolase 3;phosphatidylcholine 2-acylhydrolase GIII;sPLA2-III;SPLA2III
Extra Details:
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer&apos,s disease. [provided by RefSeq, Apr 2014]
Shipping Conditions:
Blue Ice