E-AB-91864
ABHD12 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91864
- Additional Names:
- ABHD12,ABHD12A,BEM46L2,C20orf22,PHARC,dJ965G21.2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ABHD12
- Uniprot:
- Q8N2K0
- Synonyms:
- 2-arachidonoylglycerol hydrolase;2-arachidonoylglycerol hydrolase ABHD12;ABHD12A;abhydrolase domain-containing protein 12;BEM46L2;C20orf22;dJ965G21.2;hABHD12;lysophosphatidylserine lipase ABHD12;monoacylglycerol lipase ABHD12;oxidized phosphatidylserine lipase ABHD12;PHARC
- Extra Details:
- This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
- Shipping Conditions:
- Blue Ice