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E-AB-91843

SP140 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-91843
Additional Names:
LYSP100,LYSP100-A,LYSP100-B,SP140
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SP140
Uniprot:
Q13342
Synonyms:
lymphoid-restricted homolog of Sp100;lymphoid-specific SP100 homolog;LYSP100;LYSP100-A;LYSP100-B;nuclear autoantigen Sp-140;nuclear body protein SP140;speckled 140 kDa
Extra Details:
This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn&apos,s disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
Shipping Conditions:
Blue Ice