E-AB-91805
Proteinase 3/PR3 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91805
- Additional Names:
- ACPA,AGP7,C-ANCA,CANCA,MBN,MBT,NP-4,NP4,P29,PR-3,PR3,PRTN3
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human Proteinase 3/PR3
- Uniprot:
- P24158
- Synonyms:
- ACPA;AGP7;azurophil granule protein 7;C-ANCA;C-ANCA antigen;CANCA;leukocyte proteinase 3;MBN;MBT;myeloblastin;neutrophil proteinase 4;NP-4;NP4;P29;PR-3;PR3;serine proteinase, neutrophil;wegener autoantigen;Wegener granulomatosis autoantigen
- Extra Details:
- Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.
- Shipping Conditions:
- Blue Ice