E-AB-91703
KAT6B Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91703
- Additional Names:
- GTPTS,KAT6B,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human KAT6B
- Uniprot:
- Q8WYB5
- Synonyms:
- GTPTS;histone acetyltransferase KAT6B;histone acetyltransferase MORF;histone acetyltransferase MOZ2;histone acetyltransferase MYST4;K(lysine) acetyltransferase 6B;monocytic leukemia zinc finger protein-related factor;MORF;MOZ-related factor;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MOZ2;MYST histone acetyltransferase (monocytic leukemia) 4;MYST-4;MYST4;qkf;querkopf;ZC2HC6B
- Extra Details:
- The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice