E-AB-91536
PPFIBP1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91536
- Additional Names:
- L2,PPFIBP1,SGT2,hSGT2,hSgt2p
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PPFIBP1
- Uniprot:
- Q86W92
- Synonyms:
- hSGT2;hSgt2p;L2;liprin related protein;liprin-beta-1;Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1;protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1;PTPRF interacting protein, binding protein 1 (liprin beta 1);PTPRF-interacting protein-binding protein 1;SGT2
- Extra Details:
- The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Shipping Conditions:
- Blue Ice