E-AB-91473
D2HGDH Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91473
- Additional Names:
- D2HGD,D2HGDH
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human D2HGDH
- Uniprot:
- Q8N465
- Synonyms:
- D-2-hydroxyglutarate dehydrogenase, mitochondrial;D2HGD
- Extra Details:
- This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
- Shipping Conditions:
- Blue Ice