E-AB-91452
RNF185 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91452
- Additional Names:
- RNF185
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RNF185
- Uniprot:
- Q96GF1
- Synonyms:
- BSK65-MONO1;BSK65-MONO2;BSK65-PANC1;BSK65-PANC2;BSK65-TEST1;BSK65-TEST2;BSK65-TEST3;E3 ubiquitin-protein ligase RNF185;RING finger protein 185;RING-type E3 ubiquitin transferase RNF185
- Extra Details:
- E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER-associated degradation (ERAD pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.
- Shipping Conditions:
- Blue Ice