E-AB-91370
ACMSD Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91370
- Additional Names:
- ACMSD
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ACMSD
- Uniprot:
- Q8TDX5
- Synonyms:
- 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;picolinate carboxylase
- Extra Details:
- The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase, EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
- Shipping Conditions:
- Blue Ice