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E-AB-91213

KIF7 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-91213
Additional Names:
ACLS,AGBK,HLS2,JBTS12,KIF7,UNQ340
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human KIF7
Uniprot:
Q2M1P5
Synonyms:
ACLS;AGBK;EQYK340;HLS2;JBTS12;kinesin-like protein KIF7;UNQ340
Extra Details:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Shipping Conditions:
Blue Ice