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E-AB-91138

PRG4 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-91138
Additional Names:
CACP,HAPO,JCAP,MSF,PRG4,SZP
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PRG4
Uniprot:
Q92954
Synonyms:
articular superficial zone protein;CACP;HAPO;hemangiopoietin;JCAP;lubricin;megakaryocyte stimulating factor;Megakaryocyte-stimulating factor;MSF;proteoglycan 4;superficial zone proteoglycan;SZP
Extra Details:
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice