TFB1M Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-91077
Additional Names:: CGI-75,CGI75,TFB1M,mtTFB,mtTFB1
Application:: WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TFB1M
Uniprot:: Q8WVM0
Synonyms:: CGI-75;CGI75;dimethyladenosine transferase 1, mitochondrial;h-mtTFB1;homolog of yeast mitochondrial transcription factor B;hTFB1M;mitochondrial 12S rRNA dimethylase 1;mitochondrial dimethyladenosine transferase 1;Mitochondrial transcription factor B1;mtTFB;mtTFB1;S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
Extra Details:: The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).