E-AB-91027
GP6 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-91027
- Additional Names:
- BDPLT11,GP6,GPIV,GPVI
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human GP6
- Uniprot:
- Q9HCN6
- Synonyms:
- BDPLT11;glycoprotein 6;GPIV;GPVI;platelet collagen receptor;platelet glycoprotein VI
- Extra Details:
- This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice