E-AB-90891
BSCL2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90891
- Additional Names:
- BSCL2,GNG3LG,HMN5,PELD,SPG17,seipin
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BSCL2
- Uniprot:
- Q96G97
- Synonyms:
- Berardinelli-Seip congenital lipodystrophy 2 (seipin);Bernardinelli-Seip congenital lipodystrophy type 2 protein;BSCL2, seipin lipid droplet biogenesis associated;GNG3LG;HMN5;HMN5C;PELD;seipin;SPG17
- Extra Details:
- This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
- Shipping Conditions:
- Blue Ice