(KO Validated) CRMP2/DPYSL2 Polyclonal Antibody

Size

£210.60

Was £234.00

SKU:: E-AB-90888
Additional Names:: CRMP-2,CRMP2,DHPRP2,DPYSL2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2
Application:: IHC, WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human CRMP2/CRMP2/DPYSL2
Uniprot:: Q16555
Synonyms:: Collapsin response mediator protein 2;collapsin response mediator protein hCRMP-2;CRMP-2;CRMP2;DHPRP2;dihydropyrimidinase-related protein 2;DRP-2;DRP2;N2A3;ULIP-2;ULIP2;unc-33-like phosphoprotein 2
Extra Details:: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.