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E-AB-90677

SULF1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90677
Additional Names:
SULF-1,SULF1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SULF1
Uniprot:
Q8IWU6
Synonyms:
extracellular sulfatase Sulf-1;SULF-1;sulfatase FP
Extra Details:
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice