E-AB-90634
TLE1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90634
- Additional Names:
- ESG,ESG1,GRG1,TLE1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TLE1
- Uniprot:
- Q04724
- Synonyms:
- E(Sp1) homolog;enhancer of split groucho-like protein 1;ESG;ESG1;GRG1;transducin like enhancer of split 1;transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila);transducin-like enhancer protein 1
- Extra Details:
- Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
- Shipping Conditions:
- Blue Ice