E-AB-90589
PRDM2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90589
- Additional Names:
- HUMHOXY1,KMT8,KMT8A,MTB-ZF,PRDM2,RIZ,RIZ1,RIZ2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human PRDM2
- Uniprot:
- Q13029
- Synonyms:
- GATA-3 binding protein G3B;GATA-3-binding protein G3B;HUMHOXY1;KMT8;KMT8A;lysine N-methyltransferase 8;MTB-ZF;MTE-binding protein;PR domain 2;PR domain containing 2, with ZNF domain;PR domain zinc finger protein 2;PR domain-containing protein 2;retinoblastoma protein-binding zinc finger protein;retinoblastoma protein-interacting zinc finger protein;RIZ;RIZ1;RIZ2;zinc finger protein RIZ;zinc-finger DNA-binding protein
- Extra Details:
- This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice