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E-AB-90582

LOXL4 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:
E-AB-90582
Additional Names:
LOXC,LOXL4
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human LOXL4
Uniprot:
Q96JB6
Synonyms:
LOXC;lysyl oxidase homolog 4;lysyl oxidase related C;lysyl oxidase-like 4 pseudogene;lysyl oxidase-like protein 4;lysyl oxidase-related protein C
Extra Details:
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Shipping Conditions:
Blue Ice