E-AB-90565
MPZL1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90565
- Additional Names:
- MPZL1,MPZL1b,PZR,PZR1b,PZRa,PZRb
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MPZL1
- Uniprot:
- O95297
- Synonyms:
- immunoglobulin family transmembrane protein;MPZL1b;myelin protein zero-like protein 1;protein zero related;Protein zero-related;PZR;PZR1b;PZRa;PZRb
- Extra Details:
- Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
- Shipping Conditions:
- Blue Ice