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E-AB-90542

P2RX3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90542
Additional Names:
P2RX3,P2X3
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human P2RX3
Uniprot:
P56373
Synonyms:
ATP receptor;P2X purinoceptor 3;P2X receptor, subunit 3;P2X3;Purinergic receptor;purinergic receptor P2X, ligand gated ion channel, 3;purinergic receptor P2X3;purinoceptor P2X3
Extra Details:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Shipping Conditions:
Blue Ice