E-AB-90481
EBF1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90481
- Additional Names:
- COE1,EBF,EBF1,O/E-1,OLF1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human EBF1
- Uniprot:
- Q9UH73
- Synonyms:
- COE1;Collier, Olf and EBF transcription factor 1;early B cell factor 1;Early B-cell factor;EBF;O/E-1;OLF1;olfactory neuronal transcription factor 1;transcription factor COE1
- Extra Details:
- Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity.
- Shipping Conditions:
- Blue Ice