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E-AB-90457

ERCC3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90457
Additional Names:
BTF2,ERCC3,GTF2H,RAD25,TFIIH,TTD2,XPB
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ERCC3
Uniprot:
P19447
Synonyms:
basic transcription factor 2 89 kDa subunit;BTF2;BTF2 p89;DNA excision repair protein ERCC-3;DNA repair helicase;DNA repair protein complementing XP-B cells;excision repair cross-complementation group 3;excision repair cross-complementing rodent repair deficiency, complementation group 3;general transcription and DNA repair factor IIH helicase subunit XPB;GTF2H;RAD25;Ssl2;TFIIH;TFIIH 89 kDa subunit;TFIIH basal transcription factor complex 89 kDa subunit;TFIIH basal transcription factor complex helicase XPB subunit;TFIIH p89;TFIIH subunit XPB;TTD2;xeroderma pigmentosum group B-complementing protein;xeroderma pigmentosum, complementation group B;XPB
Extra Details:
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice