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E-AB-90363

GLIS3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90363
Additional Names:
GLIS3,NDH,ZNF515
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human GLIS3
Uniprot:
Q8NEA6
Synonyms:
GLI-similar 3;NDH;OK/KNS-cl.4;zinc finger protein 515;zinc finger protein GLIS3;ZNF515
Extra Details:
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
Shipping Conditions:
Blue Ice