E-AB-90328
RNF4 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-90328
- Additional Names:
- RES4-26,RNF4,SLX5,SNURF
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RNF4
- Uniprot:
- P78317
- Synonyms:
- E3 ubiquitin ligase RNF4;E3 ubiquitin-protein ligase RNF4;RES4-26;RING finger protein 4;RING-type E3 ubiquitin transferase RNF4;SLX5;small nuclear RING finger protein;SNURF
- Extra Details:
- The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
- Shipping Conditions:
- Blue Ice