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E-AB-90235

CRB1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90235
Additional Names:
CRB1,LCA8,RP12
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CRB1
Uniprot:
P82279
Synonyms:
CRB1-A;CRB1-B;CRB1-C;crumbs 1, cell polarity complex component;crumbs family member 1, photoreceptor morphogenesis associated;LCA8;protein crumbs homolog 1;RP12
Extra Details:
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.
Shipping Conditions:
Blue Ice