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E-AB-90184

ULBP1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-90184
Additional Names:
N2DL-1,NKG2DL1,RAET1I,ULBP1
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ULBP1
Uniprot:
Q9BZM6
Synonyms:
alcan-beta;N2DL-1;NKG2D ligand 1;NKG2DL1;RAET1I;retinoic acid early transcript 1I;UL16-binding protein 1
Extra Details:
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice