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E-AB-90052

POU2F3 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:
E-AB-90052
Additional Names:
Epoc-1,OCT-11,OCT11,OTF-11,PLA-1,PLA1,POU2F3,Skn-1a
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human POU2F3
Uniprot:
Q9UKI9
Synonyms:
Epoc-1;OCT-11;OCT11;octamer-binding protein 11;octamer-binding transcription factor 11;OTF-11;PLA-1;PLA1;POU domain transcription factor OCT11a;POU domain, class 2, transcription factor 3;Skn-1a;transcription factor PLA-1;transcription factor Skn-1
Extra Details:
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice