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E-AB-90030

PDK1/PDHK1 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:
E-AB-90030
Additional Names:
PDK1
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human PDK1/PDHK1
Uniprot:
Q15118
Synonyms:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial;mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1;PDH kinase 1;pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial;Pyruvate dehydrogenase kinase isoform 1;pyruvate dehydrogenase kinase, isoenzyme 1
Extra Details:
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Shipping Conditions:
Blue Ice