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E-AB-81603

Recombinant RENT1 Monoclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-81603
Additional Names:
ATP dependent helicase RENT1,ATP-dependent helicase RENT1,Delta helicase,FLJ43809,FLJ46894,HUPF 1,KIAA0221,NORF 1,NORF1,Nonsense mRNA reducing factor 1,RENT 1,RENT1,Regulator of nonsense transcripts 1,Smg 2,Smg 2 homolog nonsens,hUpf1,pNORF 1,pNORF1
Application:
IHC, WB, IHC-P, IF
Concentration:
300 ug/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
A synthetic peptide of human RENT1
Clone:
R02-2E6
Uniprot:
Q92900
Synonyms:
ATP-dependent helicase RENT1;delta helicase;HUPF1;nonsense mRNA reducing factor 1;NORF1;pNORF1;regulator of nonsense transcripts 1;RENT1;smg-2;smg-2 homolog, nonsense mediated mRNA decay factor;up-frameshift mutation 1 homolog;up-frameshift suppressor 1 homolog;UPF1 regulator of nonsense transcripts homolog;UTF;yeast Upf1p homolog
Extra Details:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons.This protein is located only in the cytoplasm.When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Use of multiple polyadenylation sites has been noted for this gene.
Shipping Conditions:
Blue Ice