E-AB-81597
Recombinant PKR Monoclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-81597
- Additional Names:
- EIF2AK1,EIF2AK2,Eif2ak2,PKR,PPP1R83,PRKR
- Application:
- WB
- Concentration:
- 300 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- Recombinant protein of mouse PKR
- Clone:
- R04-3F2
- Uniprot:
- Q03963
- Synonyms:
- 2310047A08Rik;4732414G15Rik;AI467567;AI747578;dsRNA-activated kinase;eIF-2 alpha;eIF-2A protein kinase 2;Eukaryotic translation initiation factor 2-alpha kinase 2;IFN- type I-induced and dsRNA-activated kinase;IFN-induced and double-stranded RNA-activated kinase;interferon-induced, double-stranded RNA-activated protein kinase;interferon-inducible RNA-dependent protein kinase;P;P1/eIF-2A protein kinase;p68 kinase;Pkr;Prkr;protein kinase R;protein kinase RNA-activated;protein kinase, interferon-inducible double stranded RNA dependent;serine/threonine-protein kinase TIK;T-cell viral integration site;Ti;Tik;tyrosine-protein kinase EIF2AK2
- Extra Details:
- The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice