Recombinant mtTFA Monoclonal Antibody

Size

£178.20

Was £198.00

SKU:: E-AB-81584
Additional Names:: Mitochondrial transcription factor 1,MtTF1,TCF 6,TCF-6,TCF6,TCF6L1,TCF6L2,TCF6L3,TFAM,Tra,Transcription factor 6,Transcription factor 6 like 2 (mitochondrial transcription factor),anscription factor 6-like 1,mitochondrial transcription factor A,mtTFA
Application:: IHC, WB, IHC-P, IF
Concentration:: 300 ug/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:: A synthetic peptide of human mtTFA
Clone:: R08-3E2
Uniprot:: Q00059
Synonyms:: mitochondrial transcription factor 1;mitochondrial transcription factor A;MTDPS15;MTTF1;MTTFA;TCF6;TCF6L1;TCF6L2;TCF6L3;transcription factor 6;transcription factor 6-like 1;Transcription factor 6-like 2;transcription factor 6-like 2 (mitochondrial transcription factor);transcription factor 6-like 3;transcription factor A, mitochondrial
Extra Details:: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.

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