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E-AB-81492

Recombinant TRIM25 Monoclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-81492
Additional Names:
E3 ubiquitin/ISG15 ligase TRIM25,EFP,Estrogen responsive finger protein,Estrogen-responsive finger protein,RING finger protein 147,RNF 147,RNF147,TRI25,TRIM 25,Trim25,Tripartite m,Tripartite motif containing 25,Tripartite motif containing protein 25
Application:
WB, IF
Concentration:
300 ug/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
A synthetic peptide of human TRIM25
Clone:
R06-1H2
Uniprot:
Q14258
Synonyms:
E3 ubiquitin/ISG15 ligase TRIM25;EFP;estrogen-responsive finger protein;RING finger protein 147;RING-type E3 ubiquitin transferase;RING-type E3 ubiquitin transferase TRIM25;RNF147;tripartite motif protein TRIM25;tripartite motif-containing protein 25;ubiquitin/ISG15-conjugating enzyme TRIM25;Z147;Zinc finger protein 147;zinc finger protein 147 (estrogen-responsive finger protein);zinc finger protein-147;ZNF147
Extra Details:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Shipping Conditions:
Blue Ice