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E-AB-81473

Recombinant GSDMD Monoclonal Antibody

Size

£178.20

Was £198.00

SKU:
E-AB-81473
Additional Names:
DF5L,DFNA5L,FKSG10,GSDMD,GSDMDC1
Application:
WB
Concentration:
300 ug/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
Recombinant protein of human GSDMD
Clone:
R06-5C5
Uniprot:
P57764
Synonyms:
DF5L;DFNA5L;FKSG10;gasdermin domain containing 1;gasdermin domain-containing protein 1;gasdermin-D;GSDMDC1
Extra Details:
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1B Beta secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Shipping Conditions:
Blue Ice