E-AB-81470
Recombinant FTO Monoclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-81470
- Additional Names:
- ALKBH9,AW743446,AlkB homolog 9,Alpha-ketoglutarate-dependent dioxygenase FTO,FATSO,FTO,Fat mass and obesity-associated protein,Fto,GDFD,HOMOLOG OF,KIAA1752,MOUSE,Protein fatso,mKIAA1752
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 300 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human FTO
- Clone:
- R06-8G5
- Uniprot:
- Q9C0B1
- Synonyms:
- AlkB homolog 9;ALKBH9;alpha-ketoglutarate-dependent dioxygenase FTO;BMIQ14;fat mass and obesity associated;fat mass and obesity-associated protein;GDFD;m6A(m)-demethylase FTO;mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO;mRNA N(6)-methyladenosine demethylase FTO;tRNA N1-methyl adenine demethylase FTO;U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO;U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
- Extra Details:
- This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
- Shipping Conditions:
- Blue Ice